冯林老师团队主要集中在多场控制的微纳米机器人方面研究。微纳米机器人难题在于如何实现高精度无污染、非接触操作，针对这些难题课题组主要取得以下成果：（1） 率先提出了基于活细胞的磁控细胞机器人，可以进入血液循环系统并完成实体肿瘤的杀伤，论文发表在Small，AIS，Lab chip等封面文章；（2）提出零摩擦、非接触磁场和超声悬浮耦合驱动新方法，发表在机嚣人顶级杂志IJRR，APL，JAP等；（3）实现基于微机器人的细胞克隆流水线加工方法发表在芯片上实验室Lab chip，Biomicrofluidics，IJMS，Advanced Intelligent System.等杂志；谷歌学术他引700多次。相关研究在国际机器人大会ICRA，IROS等获奖9次，2019年开始一直担任微纳机器人分会编委以及分会主席。 2013年获得JSPS学者，2016年获得北航“卓越百人”，2018年获得北航“青年拔尖人才”资助，2019年获得“北京市科技新星”，2019年获批国家重点研发智能机器人专项“靶向药物输送场控微纳米机器人精准化技术与医用基础研究”重大课题资助。累计发表中英文学术论文100余篇，出版教材一部《微纳米机器人概论》，出版英文合著一部《Field-controlled micro-nano manipulations and micro-nano robots》，SCI论文50余篇，Small封面一篇，Lab chip封面二篇，Advanced Intelligent System封面一篇，IEEE国际会议论文共计50多篇。负责、参与国家以及省部级重大项目15余项。研究主要集中在场控微纳载药机器人，建立靶向药物输送微纳机器人一体化制造与多场驱动技术体系，为新一代微纳米机器人制备及控制提供理论及方法支持。细胞生物学、生物制造以及再生医疗等领域中，细胞组织级的精密操作显得极为重要，比如克隆、体外受精、人工诱导多能干细胞生长成型等。传统的细胞操纵方法大多采用体积庞大的微操作机械臂，其精度低、可重复性低、价格昂贵、效率低下。因此为了解决这一几十年不变的陈旧技术，我们设计开发出了新型磁控微型机器人，应用于单细胞操作。其具有精度高、控制简单、可重复性高等优势。该微型机器人由磁性材料加工而成，封装于微流控芯片中，通过利用外界磁场的自动化控制，可以有效避免外界环境对细胞的侵染，并极大的提高了操作控制精度。 ___·主持课题与项目·__________________________________________________________ 主持或参加的主要科研项目（按时间顺序倒排） 1. 胶囊机器人系统研究，2019年-2023年，横向课题，50万 2. 光电操作设备中核心光电薄膜的研制，2020年-2021年，横向课题，100万 3. 国家重点研发计划 靶向药物输送场控微纳机器人基础研究 453万 4. 2019-nCoV快速诊断技术与互联网+AI预防控制体系, 子课题负责人 100万 5. “JCJQ计划”重点基础研究项目（GF973计划），2019-JCJQ-ZD-120-00，基于植入式芯片与光电**脊髓功能重塑技术研究，2019-12至2022-12，1200万在研，参与 6. 北京市科技新星项目 靶向给药场控微纳米机器人技术 2019.11-2021.11 50万 7. 北京市自然基金针对细胞级微纳米机器人系统研究 2017.10-2020.6 28万 8. 科技委仿生悬停平台器件研究及演示验证2017.7-2018.6 750万 9. 科技委仿生智能变色光子晶体纳驱动2017.8-2019.7 100万 10. 人才 青年拔尖人才计划 2018-2021 100万 11. 人才 卓越百人科研启动经费 2016.10-2017.12 50万 12. 人才 仿生多级结构多场效应创新团队 2017.8-2018.7 100万 13. 基础研究文部科学省Challenge of On-chip Precise Enucleation of Oocyte Using 3D 6DOF Manipulation 2013.4-2015.3 4,030,000日元 14. 基础研究文部科学省 Autonomous induction monitoring and cell measurement by ultra-high-speed operation 2013.4-2014.3 122,720,000日元 15. Nagoya Univ. GCOE High Speed Enucleation of Oocyte Using Magnetically Actuated Microrobot on a Chip 2013.4-2014.3 1,000,000日元 16. 基础研究科技振兴会 Automatic oocyte enucleation manipulation 2011.4-2013.3 2,000,000日元 17. 基础研究文部科学省 Evaluation and dynamic measurement of biomembrane transporter using on-chip 2008.4-2010.3 49,790,000日元 ___·学术期刊·_______________________________________________________________ [1] Zhang, Wei; Song, Bin; Bai, Xue; Jia, Lina; Song, Li; Guo, Jingli; Feng, Lin*, (2021). Versatile acoustic manipulation of micro-object using mode-switchable oscillating bubbles: transportation, trapping, rotation, and revolution. Lab on a Chip [2] Liang, Shuzhang; Gan, Chunyuan; Dai, Yuguo; Zhang, Chaonan; Bai, Xue; Zhang, Shuailong; Wheeler, Aaron; Chen, Huawei; Feng, Lin*, (2021). Interaction between Positive and Negative Dielectric Microparticles / Microorganism in Optoelectronic Tweezers. Lab on a Chip [3] Dai, Y., Bai, X., Jia, L., Sun, H., Feng, Y., Wang, L., ... & Feng, Lin* (2021). Precise Control of Customized Macrophage Cell Robot for Targeted Therapy of Solid Tumors with Minimal Invasion. Small, 2103986. (封面) [4] Xue Bai, Dixiao Chen, Yuguo Dai, Shuzhang Liang, Bin song, Jiurong Guo, Bofang Dai, Deyuan Zhang, Feng, Lin*, Bone formation recovery with gold nanoparticle-induced M2 macrophage polarization in mice, Nanomedicine: Nanotechnology, Biology and Medicine, 2021, 102457 [5] Bai, X. , Song, B. , Chen, Z. , Zhang, W. , & Feng, Lin*. (2021). Postoperative evaluation of tumour based on label-free acoustic separation of circulating tumour cells by microstreaming. Lab on a Chip. (封面) [6] Zhou, X. , Zhang, D. , Huang, Z. , Song, X. , Liu, H. , & Feng, Lin* . Liftoff of a new hovering oscillating-wing micro aerial vehicle. Bionic Engineering, 18(3), 13. [7] Chen, D. , Yang, Z. , Ji, Y. , Dai, Y. , & Arai, F. Feng, Lin* (2021). Deformable ferrofluid-based millirobot with high motion accuracy and high output force. Applied Physics Letters, 118(13), 134101. [8] Liang, S. , Cao, Y. , Dai, Y. , Wang, F. , & Feng, Lin* . A versatile optoelectronic tweezer system for micro-objects manipulation: transportation, patterning, sorting, rotating and storage. Micromachines, 12(3), 271. 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Yan, Xing; Gong, Longlong; Wang, Feifei; Xu, Yuanhang; Feng, Lin*; Zhang, Deyuan; Jiang, Yonggang; Improved Piezoelectric Sensing Performance of P (VDF–TrFE) Nanofibers by Utilizing BTO Nanoparticles and Penetrated Electrodes ACS applied materials & interfaces 11 7 7379-7386 2019 ACS Publications [22] Feng, Lin*; Chen, Dixiao; Zhou, Qiang; Song, Bin; Zhang, Wei; Cell Injection Microrobot Development and Evaluation in Microfluidic Chip 2019 International Conference on Robotics and Automation (ICRA) 4831-4836 2019 IEEE [23] Gong, De; Cai, Jun; Celi, Nuoer; Liu, Chang; Zhang, Wenqiang; Feng, Lin*; Zhang, Deyuan; Controlled propulsion of wheel-shape flaky microswimmers under rotating magnetic fields Applied Physics Letters 114 12 123701 2019 AIP Publishing LLC [24] Song, Li; Yang, Xiuping; Hu, Hang; Peng, Guanya; Wei, Wenxuan; Dai, Yuguo; Feng, Lin*; The Design of 3-D Space Electromagnetic Control System for High-Precision and Fast-Response Control of Capsule Robot with 5-DOF International Conference on Intelligent Robotics and Applications 202-212 2019 Springer [25] Wang, Xu; 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Feng, Lin*; Mousa, Abdulhamid M; Ullah, Zakir; Masoud, Mohamed Ahmed; A Capsule-Type Device for Soft Tissue Cutting Using a Threadless Ballscrew Actuator 2019 International Conference on Manipulation, Automation and Robotics at Small Scales (MARSS) 1月6日 2019 IEEE [30] Li, Zeming; Zhang, Deyuan; Wang, Dongyue; Zhang, Liwen; Feng, Lin*; Zhang, Xiangyu; A Bioinspired Flexible Film Fabricated by Surface-Tension-Assisted Replica Molding for Dynamic Control of Unidirectional Liquid Spreading ACS applied materials & interfaces 11 51 48505-48511 2019 American Chemical Society [31] Feng, Lin*; Shi, Wan-Yuan; Shoji, Eita; Kubo, Masaki; Tsukada, Takao; Effects of vertical, horizontal and rotational magnetic fields on convection in an electromagnetically levitated droplet International Journal of Heat and Mass Transfer 130 787-796 2019 Pergamon [32] Hu, Hang; Yang, Xiuping; Song, Li; Wei, Wenxuan; Peng, Guanya; Feng, Lin*; High Position Accuracy and 5 Degree Freedom Magnetic Driven Capsule Robot 2019 WRC Symposium on Advanced Robotics and Automation (WRC SARA) 19-24 2019 IEEE [33] Dai, Yuguo; Chen, Dixiao; Liang, Shuzhang; Song, Li; Qi, Qi; Feng, Lin*; A magnetically actuated octopus-like robot capable of moving in 3D space 2019 IEEE International Conference on Robotics and Biomimetics (ROBIO) 2201-2206 2019 IEEE [34] Song, Bin; Feng, Yanmin; Zhou, Qiang; Feng, Lin*; On-Chip Three-dimension Cell Rotation Using Whirling Flows Generated by Oscillating Asymmetrical Microstructures 2019 IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS) 678-683 2019 IEEE [35] Chen, Dixiao; Zhang, Wei; Dai, Yuguo; Feng, Yanmin; Chen, Yuanyuan; Bai, Xue; Feng, Lin*; 4 DOF High-speed Cell Manipulation Magnetic-tweezers and the Operating System Driven by Piezo Ceramics 2019 International Symposium on Micro-NanoMechatronics and Human Science (MHS) 1月3日 2019 IEEE [36] Dai, Yuguo; Chen, Yuanyuan; Feng, Yanmin; Chen, Dixiao; Bai, Xue; Feng, Lin*; Magnetized Cell-robot Propelled by Regular Tetrahedron Magnetic Actuation System 2019 International Symposium on Micro-NanoMechatronics and Human Science (MHS) 1月3日 2019 IEEE [37] Yanmin, Feng; 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